Tupac Shakur
Ezekiel 'Spoon' Whitmore
Tim Roth
Alexander 'Stretch' Rawland
Thandiwe Newton
Barbara 'Cookie' Cook
Charles Fleischer
Mr. Woodson
Howard Hesseman
Blind Man
Vondie Curtis-Hall
D-Reper
John Sayles
Cop #1
Lucy Liu
Cee-cee
Bokeem Woodbine
Mud (uncredited)
Kasi Lemmons
Madonna
Tom Towles
D-Reper's Henchman
