Michael Moriarty
Henry Wiggen
Robert De Niro
Bruce Pearson
Vincent Gardenia
Dutch Schnell
Phil Foster
Joe
Ann Wedgeworth
Katie
Patrick McVey
Bruce's Father
Heather MacRae
Holly
Selma Diamond
Tootsie
Barbara Babcock
Team Owner
Tom Ligon
Piney
Marshall Efron
Bradley
Hector Elias
Diego
Tom Signorelli
Goose
Nicolas Surovy
Aleck Olson
Danny Aiello
Horse
Barton Heyman
Red
Alan Manson
Doc Loftus
Pierrino Mascarino
Sid Goldman
Maurice Rosenfield
Team Owner
Andy Jarrell
Ugly
Donny Burks
Perry
James Donahue
Canada
Hector Troy
George
Tony Major
Jonah
Jack Hollander
Tegwar Player
Lou Girolami
Tegwar Player
Ernesto Gonzalez
Dr. Chambers
Arnold Kapnick
Detective
Jean David
Dutch's Wife
Beatrice Manley
Joe's Wife (as Bea Blau)
Herb Henry
Keith Crane
Dorothy Neubert
Bruce's Mother
Kaydette Grant
Gem
Dell Bethel
Third Base Coach
Vince Camuto
Baseball Player
Jeff Sartorius
Baseball Player
Willie Lemmey
Baseball Player
Doug Major
Baseball Player
Forrest Wynne
Bat Boy