Lupita Nyong'o
Adelaide Wilson / Red
Winston Duke
Gabe Wilson / Abraham
Elisabeth Moss
Kitty Tyler / Dahlia
Tim Heidecker
Josh Tyler / Tex
Shahadi Wright Joseph
Zora Wilson / Umbrae
Evan Alex
Jason Wilson / Pluto
Yahya Abdul-Mateen II
Russell Thomas / Weyland
Anna Diop
Rayne Thomas / Eartha
Cali Sheldon
Becca Tyler / Io
Noelle Sheldon
Lindsey Tyler / Nix
Madison Curry
Young Adelaide Wilson / Young Red
Napiera Groves
Dr. Foster
Duke Nicholson
Danny / Tony
Dustin Ybarra
Troy / Brand
Kara Hayward
Nancy / Syd
Jordan Peele
Dying Rabbit / Fun House Narrator (voice) (uncredited)
Darrel Cherney
News Anchor (uncredited)
Ashley McKoy
Teenage Adelaide Wilson / Teenage Red
Lon Gowan
Don
Alan Frazier
Ferdie / Jeremiah
Nathan Harrington
Glen / Jack
James Cobb
Don (uncredited)
Alessandro Garcia
EMT (uncredited)
David M Sandoval Jr.
Father of Family on Beach (uncredited)
