Anne Bancroft
Annie Sullivan
Victor Jory
Captain Arthur Keller
Inga Swenson
Kate Keller
Andrew Prine
James Keller
Kathleen Comegys
Aunt Ev
Patty Duke
Helen Keller
John Bliss
Admissions Officer (uncredited)
Judith Lowry
1st Crone (uncredited)
Beah Richards
Viney (uncredited)
Grant Code
Doctor (uncredited)
Michele Farr
Annie at Age 10 (uncredited)
Jack Hollander
Mr. Anagnos of Perkins School in Boston (uncredited)
Alan Howard
Jimmie at Age 8 (uncredited)
William F. Haddock
2nd Crone (uncredited)
Helen Ludlam
3rd Crone (uncredited)